Understanding How Whey Protein & Whey Protein Isolate Differ (2024)

Commonly used by athletes, fitness enthusiasts, and those looking to increase protein intake, whey protein is highly valued for its digestibility and rapid absorption in the body, making it an effective option for post-workout recovery.

Whey protein is available in several forms:

  • Whey protein concentrate : Contains a moderate amount of fats and carbohydrates and is often more affordable.

  • Whey protein isolate : Processed to remove most of the fats and carbohydrates, resulting in a higher protein concentration.

  • Whey protein hydrolysate : Pre-digested for faster absorption and generally used in medical protein supplements and infant formulas.

Additionally, whey protein has benefits beyond muscle building, such as supporting weight loss goals, enhancing immune function, and promoting cardiovascular health.

The key differences between whey protein isolate and other types of whey protein relate to protein content, processing methods, taste, texture, and cost.

However, there’s a lot more that most people should know about when it comes to the benefits of whey protein isolate. Let’s explore the nuances between whey isolate and other whey proteins to help you choose the best supplement for your goals.


Whey Protein Overview

Whey protein is a high-quality protein derived from milk during the cheese-making process. It is a popular dietary supplement known for its rich amino acid profile, especially its abundance of branched-chain amino acids (BCAAs) that are crucial for muscle growth and repair.


How Whey Protein is Produced:

  1. Milk Separation: Whey is a by-product of the cheese-making process. Milk is split into curds (used for cheese) and liquid whey, which is the source of whey protein.

  2. Filtration and Purification: The liquid whey undergoes a filtration process to remove fats, lactose, and other non-protein components. This filtration produces different types of whey protein.

  3. Drying and Packaging: The purified whey is dried into powder and packaged as whey protein supplements.

This process results in a protein source that is versatile, easy to digest, and effective for muscle support and recovery.

Dietary sources

Whey protein is not commonly found in whole foods because it is a specific component extracted from milk. However, some dairy-based foods naturally contain whey protein along with casein (another milk protein). Here are a few foods with natural whey protein content, along with their overall protein content per serving:

1. Milk

  • Protein Content: 8 grams per 1 cup (240 ml)

  • Milk contains a blend of casein (about 80%) and whey protein (about 20%), providing both slow- and fast-digesting proteins.

2. Greek Yogurt

3. Ricotta Cheese

  • Protein Content: 14 grams per 1/2 cup (124 grams)

  • Ricotta cheese is a soft cheese that retains more whey than harder cheeses. Its protein content includes both whey and casein.

4. Cottage Cheese

  • Protein Content: 14 grams per 1/2 cup (113 grams)

  • Cottage cheese is also rich in whey and casein proteins. It's not as concentrated in whey as ricotta but still offers some amount of both proteins.

5. Other Soft Cheeses (like Mascarpone)

  • Protein Content: 2-4 grams per ounce (28 grams), depending on the cheese type

  • Soft cheeses like mascarpone have a small amount of whey, though most of their protein comes from casein.

6. Whey Protein Powder Supplements

  • Protein Content: 20-30 grams per scoop (30 grams)

  • While not a whole food, whey protein powder supplements are derived directly from whey protein in milk and provide a concentrated source of whey protein.

Whole foods generally contain mixed proteins rather than pure whey, with casein often being the dominant type in milk-based foods. Whey protein supplements offer a direct and higher concentration source compared to foods.

Most Common Types of Whey Protein

  • Whey Protein Concentrate (WPC): Contains 70-80% protein, along with some lactose and fats.

  • Whey Protein Isolate (WPI): Further filtered to reach 90% or higher protein content, with minimal lactose and fat.

  • Whey Protein Hydrolysate: Pre-digested form, where proteins are broken down into smaller peptides for faster absorption.

Benefits

Whey protein isolate can offer a wealth of benefits, including:


  • Supporting muscle mass and strength

  • Accelerating recovery when taken post-exercise: This research looked at the effect of whey protein on muscle damage after eccentric exercise.

  • Helping improve body composition: This study looked at the benefits of whey protein on body composition after resistance training.

  • Strengthening the immune system

  • Promoting overall well-being

Whey Isolate vs Concentrate vs Hydrolysate: The Key Differences

Aspect Whey Protein Isolate Whey Protein Concentrate Whey Protein Hydrolysate
How it’s processed Processed to remove most of the fats and carbohydrates, resulting in a higher protein concentration Processed via filtration and purification methods designed to retain protein while reducing fat and lactose Proteins are broken down into smaller peptides for faster absorption
Pros
  • Highest protein content (~90%)
  • Minimal lactose and fats
  • Good absorption
  • Ideal for those on a low-carb or low-fat diet
  • More affordable
  • Typically 70-80% protein content
  • Good for those who are lactose intolerant
  • Faster absorption
  • Easier to digest
  • Ideal for medical and infant use
  • Low allergenic potential
Cons
  • More expensive
  • Contains some lactose and fats
  • Bitter taste/flavor
  • Expensive

How Isolate, Concentrate, and Hydrolysate Are Similar

Whey protein isolate, concentrate, and hydrolysate share several important similarities as they all derive from the same source (whey protein from milk) and undergo similar processing stages before they reach their final forms. Here’s how they are similar:

1. Source and Origin

All three types originate from whey, a by-product of the cheese-making process in dairy milk. They contain a similar profile of high-quality protein that includes essential amino acids and branched-chain amino acids (BCAAs), which are beneficial for muscle growth and recovery.

2. Complete Protein Profiles

Each form of whey protein is a complete protein, meaning it contains all nine essential amino acids. This makes them ideal for supporting muscle repair, growth, and overall bodily functions that require complete proteins.

3. Rapid Absorption (Compared to Other Proteins)

Whey proteins are generally fast-digesting compared to other protein sources like casein. While hydrolysate is the fastest among the three, isolate and concentrate also provide quick absorption, making all whey protein types good options for post-workout recovery.

4. High Biological Value

Whey proteins have a high biological value, meaning they are efficiently utilized by the body. All three forms are considered superior in terms of bioavailability and are readily absorbed and used for muscle repair and maintenance.

5. Versatile Use in Supplementation

Isolate, concentrate, and hydrolysate are all used in protein powders and can be included in various supplements. They are also commonly found in protein bars, ready-to-drink shakes, and other food products that aim to boost protein intake.

6. Health and Fitness Benefits

Each form of whey protein supports muscle recovery, enhances muscle synthesis, and helps with weight management and immune health due to its rich amino acid content and ease of digestion. They are all widely used by athletes, bodybuilders, and anyone looking to increase dietary protein intake.

7. Minimal Carbohydrates and Fats

Although they vary slightly, especially with concentrate containing a bit more fat and carbohydrates, all three forms have relatively low levels of these macronutrients compared to whole foods, making them efficient for pure protein intake without many extra calories.


Which Whey Protein Supplement Should You Take?

If you’re looking for the highest protein content with the best taste, fewest calories, low lactose content, and you’re not on a lean budget then whey protein isolate is likely your best option.

If you’re on a tighter budget but still looking for a high-protein source and you’re not adversely affected by lactose then whey protein concentrate is likely your best bet.

If you’re not budget conscious and looking for the fastest absorption rate then whey protein hydrolysate is likely your preferred route, although a taste test is advisable.


If you’re looking for a quality whey isolate, check out Momentous Grass-Fed Whey Protein Isolate here. It’s one of our best sellers and is used in every NFL locker room.

It delivers 20g of grass-fed protein per serving, sourced from European dairy farmers and is cold-processed to maintain an optimal amino acid profile. It boasts the addition of ProHydrolase, a proprietary blend of enzymes for better digestion and absorption.

This formula was also recently upgraded and is now free from gums, stabilizers, and refined sugars—making it the most effective and purest protein option for your daily needs. Learn more about the upgraded formula here—Our Whey Protein: Great Just Got Better.

It’s NSF and Informed Sport Certified ensuring it’s free from contaminants, heavy metals, and banned substances.

What customers are saying about Momentous Whey Protein:

“Best whey protein isolate out there! Clean, quality ingredients, great taste, and easy to digest. Great addition to smoothies or simply mixed in liquid of your choice.”

-Steve H.

“Loved this protein powder! The taste is fantastic! I mix it with cold water and it tastes like chocolate milk from my childhood. Mixes easily with no clumps and love that it’s made with high quality ingredients!”

-Carole E.


Frequently Asked Questions

Is isolate, concentrate, or hydrolysate best for muscle growth?

All three types of whey protein—isolate, concentrate, and hydrolysate—are effective for muscle growth because they provide high-quality protein with essential amino acids, especially branched-chain amino acids (BCAAs) like leucine, which plays a key role in muscle protein synthesis. However, whey protein isolate is the preferred option for lean muscle growth as it offers the highest protein content by weight with most fats and lactose removed.

Which mixes the easiest?

Whey protein isolate typically mixes the easiest of the three forms due to its finer filtration and minimal fat and carbohydrate content. It usually has minimal clumping and mixes well with water, milk, and other beverages. It’s ideal for those who want a smooth, easily blendable protein that can be quickly prepared without a blender.

How is whey protein different from casein?

Whey protein and casein are both high-quality proteins derived from milk, but they differ in absorption rates, digestibility, ideal uses, and amino acid profiles. Whey provides quick, immediate support for muscle synthesis while casein offers sustained, gradual support for muscle maintenance.

Understanding How Whey Protein & Whey Protein Isolate Differ (3)

Emma-Kate Lidbury

Emma-Kate Lidbury is a freelance writer and editor with 20 years of experience working in the health and fitness world.

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